Friday, August 3, 2012

The treatment principle for interstitial nephritis

Interstitial nephritis is the renal interstitial part of the inflammatory disease of the main lesion, lesions often involved the renal tubules, it is also known as interstitial nephropathy. Clinically can be divided into two kinds of acute and chronic interstitial nephritis, its treatment of the following principles:

(1) prevention interstitial nephritis to focus on prevention, after the removal of the general cause of the disease can stop the development of more than 90% of early cases can be fully restored. Caused by pyelonephritis, should be actively anti-infections; urinary tract obstruction caused by the obstruction should be lifted as soon as possible; caused by poison, drug, should immediately stop using these drugs or poisons, and for the appropriate treatment.

(2) The principle of treatment of acute interstitial nephritis acute interstitial nephritis, abrupt onset, as the main manifestation of renal interstitial inflammatory cell infiltration, often accompanied by impaired renal function. The main principle of treatment for the removal of the cause, such as nephrotoxic drugs is disabled from poisoning the environment, positive, infection control, treatment of immune disease, etc.; adrenal cortical hormone should be used for severe acute interstitial nephritis, and at the same time line antihypertensive diuretic, anti-allergy symptomatic treatment.

(3) the principles of treatment of chronic interstitial nephritis, chronic interstitial nephritis, insidious onset, slow progress, mainly as interstitial fibrosis and tubular atrophy. At present, no specific therapy in the western medicine treatment for different causes. Patients should pay attention to the rest, better nutrition to their own bodies; water, electrolyte and acid-base balance disorder, blood pressure control, improvement of anemia; such as the existence of urinary tract infection should actively control the infection, such as uremia dialysis treatment should be to correct.

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