Thursday, August 2, 2012

Treatment Principles for chronic renal failure


Chronic renal failure, also known as chronic renal insufficiency is a clinical syndrome that occurs in a variety of chronic kidney disease late, to stay its metabolites retention of water and electrolyte imbalance and acid-base balance disorders, severe renal damage mainly. By varying degrees of impaired renal function, renal function can be divided into decompensated renal insufficiency, azotemia (also known as renal failure early, the uremia early) and renal failure and end-stage (also known as uremia ) four, the principles of treatment are as follows:
(1) the general treatment of the general treatment including diet nursed back to health, nutrition therapy, stable environment for the body to maintain and symptomatic treatment. Low-protein diet and the diet to restore, is the most basic, the most effective measures, the application should be adjusted according to the situation. Rhubarb and its preparations, with a high metabolic state, to improve the healthy kidney tissue and reduce the residual nephron hypertrophy, and inhibit the mesangial cell proliferation, so the application can delay the process of chronic renal failure.
(2) angiotensin-converting enzyme inhibitors, such as angiotensin converting enzyme inhibitors such as captopril, according to the use of enalapril, etc., can reduce blood pressure, glomerulosclerosis and reduces proteinuria; long-term sodium bisulfate can correct acidosis, to reduce the formation of ammonia, to improve the protein and uric acid metabolism; application of phosphorus-binding agents and low-phosphorus diet, are conducive to slow down the development process of chronic renal failure.
(3) replacement therapy replacement therapy, including gastrointestinal dialysis, colorectal dialysis, peritoneal dialysis, hemodialysis, skin through near, according to disease and adapt to the indications selected. In recent years, advocates the early prevention of dialysis may be more favorable to the development of prevention and treatment of disease.
(4) kidney transplantation in the treatment of renal transplantation in the treatment of end-stage chronic renal failure, according to the indications application.

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