Classification and Treatment of lupus nephritis

"Classification and Treatment of lupus nephritis [Tags: Key words] are the majority of patients concern, Shijiazhuang kidney hospital for a brief introduction of lupus nephritis and Treatment
Lupus nephritis, systemic lupus erythematosus renal different pathological types of immune damage, there is apparently a disease clinical manifestations of kidney damage. According to the development of the disease, lupus nephritis different sub-type.Lupus nephritis How to treat it? Below to explain.
Genotyping approaches to treatment of lupus nephritis:
1, lupus nephritis type Ⅰ: lupus nephritis type Ⅰ, light microscope, normal kidney tissue structure, the use of immunofluorescence immunoglobulin and complement deposition.The prognosis of this type of lupus nephritis does not require special treatment, but still need follow-up study, to prepare for any eventuality.
2, lupus nephritis type Ⅱ: lupus nephritis type Ⅱ, this type of kidney damage in mesangial areas, including mesangial cells known as type Ⅱ A, and such are mild mesangial lesions prognosis without treatment; II type B lesions mesangial visible mesangial cells and mononuclear cell proliferation, accompanied by urine the protein 1g/24h and low complement C3 and hyperlipidemia, in the treatment of the need for between 6 weeks-March treatment, usually with prednisone 20mg / d, with the improvement in reduction of the disease remain. Lupus nephritis type Ⅱ, interstitial and vascular damage.
3, lupus nephritis type Ⅲ and type Ⅳ: pathological damage similar between the two treatment options are largely unchanged, the prognosis is more similar. Development of the two types of lupus nephritis in 10 years to end stage renal disease more than 50 percent, so we must strengthen the treatment to prolong the survival period of the two types of patients, is quite important. Under normal circumstances in the prognosis of treatment with glucocorticoids and cytotoxic drugs. The glucocorticoid prednisone-based, conventional dosage advice of a doctor, and the need to maintain a specific time we must obey the doctor's orders. If necessary time to give methylprednisolone maintenance treatment, that the efficacy and side effects.
4, lupus nephritis type Ⅴ: lupus nephritis type Ⅴ is divided into four types, Ⅴ type a compared with patients with idiopathic membranous nephropathy similar; type Ⅴ b diffuse mesangial changes; type Ⅴ c there are segments cell proliferation or segmental glomerular sclerosis; Ⅴ type d-exist with diffuse proliferative glomerulonephritis, similar to this type of performance in both clinical or histological performance and V lupus nephritis.
This type of treatment of lupus nephritis to distinguish between what are membranous lupus nephritis or diffuse lupus nephritis, distinct drugs and therapeutic approaches used in different pathological, but also on the type of symptomatic treatment.
5, lupus nephritis type Ⅵ: Ⅵ type of lupus nephritis is the end of the lupus nephritis, but only to 2% of all lupus nephritis type.
Further reading: the cause of lupus nephritis is due to kidney damage, the kidney fibrosis results. For the treatment of lupus nephritis, the best Chinese and Western medicine, micro-based traditional Chinese medicine to penetrate therapy, micro-based traditional Chinese medicine active substances can activate the function of renal intrinsic cells to reverse and restore normal cell metabolism; to improve the damaged kidney micro cycledisorders, kidney the aerobic repair environment, accelerate intrinsic renal cells to repair damage; improve the environment within the damaged kidney, and reduce the symptoms of poisoning, to create a relaxed environment for kidney repair and reconstruction; a biphasic immune conditioning function and metabolism, can control the progress of the disease, in order to lay a good foundation for the repair and reconstruction of the inherent cell damage the kidneys; nutrients, impaired kidney repair and reconstruction to accelerate the process of repair damage inherent in cells of the kidney.
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