How we cure lupus nephritis

Lupus nephritis treatment and other issues of concern are the majority of patients, Shijiazhuang kidney hospital for a brief introduction of lupus nephritis is how to treat "
First, the treatment of lupus nephritis is based on clinical manifestations, laboratory and renal biopsy data. For mild systemic lupus erythematosus. Lupus (eg, only a rash, fever or joint symptoms, etc.) and serological abnormalities, if the urine is normal, renal biopsy shows glomerular normal or mild lesions, as appropriate, non-steroidal anti-inflammatory drugs improve symptoms, generally without glucocorticoids or cytotoxic drugs, closely track changes in condition; if the urine is abnormal, renal biopsy shows glomerular focal segmental mesangial proliferation accompanied by segmental necrosis, crescent formation and focal glomerular hardened with small doses of glucocorticoid hormones (such as prednisone 20 to 40mg / d), as appropriate, plus cytotoxic drugs or Tripterygium preparations. Second, the heavy systemic lupus erythematosus (such as high fever, joint pain, weakness and / or lesions involving the serosa quickly, the heart, lungs, liver, blood-forming organs and other organ tissue) with acute nephritic syndrome or rapidly progressive nephritic syndrome, Renal biopsy showed diffuse proliferative glomerulonephritis, or crescentic glomerulonephritis, progressive loss of renal function should be given to standard hormone therapy and CTX pulse therapy; or methylprednisolone pulse therapy, daily 1,0 g static points 3 to 5 days for a course, 7 to 10 days following a moderate dose of prednisone to maintain, if necessary, repeat, generally not more than three courses. When the above method is ineffective or serious condition, plasma exchange therapy may be considered; cyclosporin trial can not be used by CTX neomycin A, mycophenolate mofetil. With acute severe renal insufficiency, severe high blood volume, heart failure when emergency dialysis, and out of danger, to create the conditions for drug treatment and gain time. Three, manifested as asymptomatic proteinuria (urine protein> 2g/24h) can be used glucocorticoids, as appropriate, and Tripterygium preparations and prednisone in combination with cytotoxic drugs, have a certain effect; asymptomatic hematuria, can be used Tripterygium preparations (conventional-dose or double dose) or CTX treatment. Conditional best choice of drugs under the renal pathological types. Was nephrotic syndrome, urine red blood cells small, stable renal function or renal biopsy showed membranous lupus nephritis, should be preferred to prednisone 0,8 ~ 1,0 mg / kg. d, 2 to 4 weeks after the results are poor, the addition of CTX, if accompanied by renal dysfunction, severe hypertension, renal biopsy showed marked hyperplasia of the glomerular or the occurrence of the pathological type of change should be given to standard hormone therapy plus CTX pulse therapy. Constant of proteinuria without systemic lupus erythematosus performance, or azotemia and renal pathology mainly to chronic degenerative conditions, generally not long-term treatment with prednisone and cytotoxic drugs. End-stage lupus nephritis with chronic renal failure. General treatment: rest, diet, diuretic, lowering blood pressure, anticoagulation and prevention of various complications, refer to the treatment of primary glomerular disease should be based on the patient's condition. Characteristics of treatment: Micro TCM herbs penetration treatment with traditional Chinese medicine syndrome differentiation can improve efficacy, reduce side effect of symptoms and western medicine in the treatment of lupus nephritis. And from the fundamental (for kidney lupus parts) to give the appropriate treatment.