Mesangial proliferative lupus glomerulonephritis

Mesangial proliferative lupus glomerulonephritis II type LGN is to exclude other classification parameters are limited to varying degrees of mesangial cells (≥ 3 / mesangial area) and mesangial matrix increase, with mesangial immune complexesdeposition, so any chronic and active disease are not classified as type Ⅱ. Immunofluorescence immunoglobulin (IgG, IgM and IgA) and complement component (c3, c4, of C1q and cracking prime) positive lead. Immune complexes in the positive immunofluorescence sold-out "phenomenon, the higher the characteristics of LN diagnosis. Immunofluorescence and electron microscopy occasionally scattered subepithelial and subendothelial deposits, but not enough to cause the light microscope, the changes in the vascular wall.
Electron microscope, visible particle type, dense deposits mainly in the mesangial area but can be extended to the subendothelial space next to the mesangial Light microscope under visible glomerular endothelial deposits, or the glomerular ball or segmental scar, should be based on the degree of extent of disease defined as Ⅲ or Ⅳ ¨. Tubulointerstitial and vascular changes in the type Ⅱ LGN is not obvious.