Prednisone treatment for lupus nephritis

Prednisone treatment of lupus nephritis effect okay? Prednisone treatment of lupus nephritis through immunosuppression to eliminate the clinical symptoms, the effect is worth it for sure, but the late effect of the majority of patients should be aware of: easy to relapse. Detail below.
Prednisone treatment of lupus nephritis by:
Anti-inflammatory effects: to reduce and prevent tissue response to inflammation, thereby reducing the performance of the inflammation. Hormone inhibition of inflammatory cells, including macrophages and white blood cells gather at the sites of inflammation, and inhibition of phagocytosis, the release of lysosomal enzymes and inflammatory chemical mediators synthesis and release.
Immunosuppressive effect: to prevent or inhibit the cell-mediated immune responses, delayed hypersensitivity reactions, reducing the T lymphocytes, monocytes, eosinophils number to reduce the binding capacity of immunoglobulin with cell surface receptors and inhibit the synthesis and release of interleukin, thereby reducing the T lymphocyte conversion to lymphoblastoid cells, and to mitigate the expansion of the primary immune response. Immune complexes can be reduced through the basement membrane, and can reduce the concentration of complement components and immunoglobulins.
Many patients have a certain effect after taking prednisone treatment, but side effects, but a temporary solution. Prednisone can only suppress the immune response, but can not clear the immune complexes, can not repair damaged renal intrinsic cells, so often repeated the phenomenon of illness. It is proposed to consider the other side effects of drugs, this Shijiazhuang kidney disease hospital on the existing basis of immunosuppressive drugs and technologies, the introduction of foreign, more suitable for immunosuppressive treatment of a range of low side effects of drugs and technologies , first to block the immune response, followed by immune tolerance. Immune complex deposition in the kidney, a short time, the Ministry may be completely eliminated, so let the body work hard to adapt to the fact that pathogenic foreign matter deposited in the kidney tissue to stop the immune response. Immune mediation stage is to enter, adjust the immune system within the work environment and enhance human immunity. On the basis of immune regulation in patients with the introduction of protective immunity stage repair of podocytes and mesangial cells. The last resort is to the immune clearance, according to the actual situation of the patient's immune adsorption, plasma exchange and blood purification.