Friday, July 27, 2012

Symptoms of lupus erythematosus


First, the onset of systemic symptoms can be acute and can be slow, the majority of early manifestation of a non-specific systemic symptoms such as fever, especially the common low-grade fever, general malaise, fatigue, weight loss and so on. Disease often slow re-appear alternately. Infection, sunlight, drugs, trauma, surgery can be induced or aggravated. , Skin and mucous membranes rash is common, about 40% of patients with typical facial erythema known as the butterfly erythema. Acute phase of edema, red color, a slight telangiectasia and phosphorus flaky desquamation, severe blisters, ulcers, skin atrophy and pigmentation. The palm-sized fish, fingertip and finger (toe) A week of erythema rash, purpura and other exposed parts of the body skin. A variety of skin lesions 80% of the total prevalence of the number of hair easy to break, may have alopecia areata. 15-20% of patients with Raynaud's phenomenon. Oral mucosal blisters, ulcers, accounting for about 12%. The small number of patients course of herpes zoster. , Joint and muscle around for more than 90% of patients with joint swelling and pain, and often the first symptom of treatment, most likely involved the hand proximal interphalangeal joints, knees, feet, condyle, and wrist joints can be involved. Mostly symmetry of the joint swelling and pain. About half of patients have morning stiffness. X-ray examination often change significantly, only a small number of patients with joint deformity. Muscle aches, and weakness are common symptoms. , Kidneys, approximately 50% of patients with clinical manifestations of kidney disease, such as proteinuria, hematuria, urinary tube, white blood cells in urine, low specific gravity urine, edema, blood pressure, blood urea nitrogen and creatinine increased almost 100, electron microscopy and immunofluorescence % had abnormal renal pathology, focal proliferation (light) (FPLN), diffuse proliferative (severe) (DPLN), membrane type (MLN), mesangial type (small variant according to the pathologic features of lupus nephritis is divided into: ) (MesLN). Various types of clinical transformation, deterioration, remission, prognosis and mortality. , Heart, about 10-50% of patients with heart attack, due to the disease itself, may be due to the long-term use of glucocorticoid therapy. Heart attack, including pericarditis, myocarditis, endocardial and valvular lesions, etc., depending on the individual lesions, the performance of chest tightness, chest pain, palpitations, enlarged heart, congestive heart failure, arrhythmias, heart murmur, a small number of death in patients with coronary artery infarction . Lung and pleural involvement or about 50%, of which approximately 10% suffering from lupus pneumonia, pleurisy and pleural effusion are the more common pulmonary parenchymal damage in the majority of interstitial pneumonia and pulmonary fibrosis, causing atelectasis and pulmonary dysfunction. Lupus pneumonitis is characterized by pulmonary the porphyritic infiltration, go to the other side, by the side of the hormone treatment can shadow to eliminate. On the basis of lupus lung damage, and often secondary bacterial infection. Nervous system nervous system damage about 20%, if there are more suggestive of a critical condition, brain damage and mental disorders, such as excited, abnormal behavior, depression, hallucinations, obsessions, and insanity. Epilepsy. Hemiplegia and subarachnoid hemorrhage were more common, accounting for 70% of nervous system damage, suggesting a severe illness, poor prognosis, spinal cord injury the incidence is about 3-4%, the clinical manifestations of paraplegia, incontinence or feeling of movement disorders , in the event
The above information on how to treat lupus nephritis. Should pay more attention for the treatment of lupus nephritis. Shijiazhuang Hospital of kidney disease in addition to the original "micro-based medicine penetrate therapy is the treatment of lupus nephritis, but also a comprehensive integration with existing kidney disease treatment, the formation of a set of of with Shijiazhuang nephropathy hospital characteristics lupus three-dimensional treatment of nephropathy, which includes the infiltration therapy of micro-based Chinese medicine as the core block renal fibrosis and repair of renal reconstruction of kidney functional unit of kidney disease treatment technology. Play a role in the protection and recovery of renal function.
Promote kidney natural cell repair and regeneration, early nephropathy "reparative therapy" the most cutting-edge technology, and make prospects more extensive treatment of lupus nephritis. If the "What is the treatment of lupus nephritis is not yet understand or have any questions on the treatment directly to the online expert consultation! Specialized expert telephone will respond to your questions.

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