Friday, July 27, 2012

The prognosis of lupus nephritis


70% had clinical manifestations of nephritis patients with systemic lupus erythematosus, almost 100% of renal pathological changes. After hormone and cyclophosphamide pulse therapy, 80% of patients with nephritis remission, no longer continue to develop. But there are still 10-20% of patients with nephritis will develop to the degree of renal failure.Whenever that time, doctors and patients there will be two approaches, one is regardless of the patient situation is how to give up aggressive treatment, to be conservative and supportive therapy.
The result is that some patients with this the return to normal renal function, but lost the best timing of treatment, had a lifetime of dialysis or kidney transplantation. Contrary to the other approach, no matter how patient be active immunosuppressive therapy, the result is the conservative treatment of some patients the wrong active treatment made it worse, worse.
Thus, professional doctors or patients should know. Which patients with renal failure, active immune therapy, renal function returned to normal, which patients need conservative and supportive treatment in order to improve symptoms, delay the patient's survival.
So, patients with lupus nephritis and renal failure there is hope to restore normal kidney function?
, Renal failure does not exceed 3 months, 65% of patients expected to return to normal renal function. But we also have 12% of patients die within six months. More than three months, the recovery rate.
2, more women than men the rate of recovery of renal function.
3, the serum creatinine value does not exceed 300m mol / L were recoverable from 80% hope. If more than 600m mol / L, only 25% of the possible.
4, the kidney to narrow, a very small chance of recovery of renal function.
If you have lupus nephritis restore their own health approach "is also not quite understand, can continue to read the following related content.

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