Sunday, July 29, 2012

Focal lupus glomerulonephritis nephritis


Focal lupus glomerulonephritis glomerulonephritis type III LGN almost all of the segmental lesions, and rarely see the ball in the initial study. Lesions showed segmental capillary proliferative lesions with or without crescent formation, necrosis of the capillary wall cellulose; in the development process can occur with focal segmental glomerulosclerosis package's capsule adhesions. Immunoglobulin in the classic mode of immunofluorescence, complement components (C3 and C1q) and light chain (inbound and K) were positive. Activity and chronic glomerular damage performance (Table 3). The activities of electron microscope immune deposits in the endothelium, visible endothelial swelling and a large number of multi-line leukocyte influx. Compared with immunofluorescence and electron microscopy to lack of sensitivity to the diagnosis of type Ⅲ LGN. Ⅲ type LGN. The renal tubules, renal interstitial, and renal vascular disease, common focal interstitial fibrosis and tubular atrophy. Type III LGN pathology report should be included in the glomerular activity and chronicity index, needed for diagnostic activity, chronic disease, the loop necrosis and crescent formation, involving the ratio of glomerular and tubulointerstitial and vascular lesions are described, which help to predict the clinical outcome.

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