Sub-type of lupus nephritis

Lupus nephritis is divided into six large, for each type of lupus nephritis, the treatment is different, the prognosis is different. The following six sub-type of lupus nephritis to explain the hope that understanding of understanding would be helpful for patients
A type of lupus nephritis
Renal tissue of lupus nephritis type Ⅰ, light microscope, normal structure, immunoglobulin and complement deposition in the use of immunofluorescence. The prognosis of this type of lupus nephritis does not require special treatment, but still need follow-up study, to prepare for any eventuality.
Two, lupus nephritis type 2
Lupus nephritis type Ⅱ, this type of renal injury in glomerular mesangial area, which no mesangial cell proliferation is known as type Ⅱ A, these are mild mesangial lesions prognosis without treatment; II B lesions mesangial area seen in mesangial cells and mononuclear cell proliferation, to urinary protein 1g/24h and low complement C3 hyperlipidemia accompanied in the treatment of the need for six weeks between -3 treatment, usually with prednisone 20mg / d, continued with the improvement in reduction of the disease remain. Lupus nephritis type Ⅱ, interstitial and vascular damage.
3 of lupus nephritis
Ⅲ type of glomerular damage in lupus nephritis has been more significant, In addition to the mesangial focal stage glomerular capillary has been involved, but no more than 50% of the total glomerular Lupus nephritis type Ⅳ and Ⅲ type of injury, but the damage is more extensive glomerular damage, up to 50% level of more serious.
Pathological damage similar between the two treatment programs similar prognosis.Development of the two types of lupus nephritis in 10 years to end stage renal disease more than 50 percent, so we must strengthen the treatment to prolong the survival period of the two types of patients, is quite important. Under normal circumstances in the prognosis of treatment with glucocorticoids and cytotoxic drugs. The glucocorticoid prednisone-based, conventional dosage advice of a doctor, and the need to maintain a specific time we must obey the doctor's orders. If necessary time to give methylprednisolone maintenance treatment, that the efficacy and side effects. Cell poison drug is also commonly used treatment, glucocorticoid with the cell poison, drug combination more fully. But the cytotoxic onset interval is longer, often 3-4 months before onset.
4, type 4 lupus nephritis
Ⅴ type of lupus nephritis is divided into four types, type Ⅴ a primary membranous nephropathy are similar; type Ⅴ b diffuse mesangial changes; type Ⅴ c there are segmental proliferation or segmental sclerosis ; Ⅴ d-exist with diffuse proliferative glomerulonephritis of this type regardless of the clinical manifestations of organizational performance is similar to the type Ⅴ lupus nephritis.
This type of treatment of lupus nephritis to distinguish between what are membranous lupus nephritis or diffuse lupus nephritis, distinct drugs and therapeutic approaches used in different pathological, but also on the type of symptomatic treatment.
5, lupus nephritis type
Ⅵ type of lupus nephritis are the end of lupus nephritis, lupus nephritis type accounts for only 2%.
The above explanation of lupus genotyping patients understanding of understanding would be helpful. Active lupus nephritis treatment.